The toxic effects of fluoroquinolone are the result of antibiotics that could cause severe, long-lasting negative side negative effects. They include nausea vomiting, diarrhea and muscle pain. It is also known as Floxing.
Patients who have suffered adverse reactions to an antibiotic that contains fluoroquinolone/quinolone must stay away from fluoroquinolones. People suffering from kidney disease, the elderly and those who have had an organ donation must be considered.
Most quinolone antibiotics that are employed are fluoroquinolones which contain a fluorine atom in their chemical structure . They are effective against Gram-positive and Gram negative bacteria.
Fluoroquinolones kill bacteria through blocking enzymes which normally break up DNA during the process of cell reproduction. The enzymes cut DNA’s doublehelix. They then pass another strand through the gap, and repair the cut.
Quinolones can bind to enzymes, thereby preventing them from fixing their cuts. In the 1980s, scientists added fluorine atoms to structure of the quinolones. This allowed the antibiotics to penetrate the body’s tissues as well as the central nervous system, and increased their effectiveness against a broad spectrum of bacterial infections.”
Fluoroquinolones can be beneficial in certain infections that are life-threatening, for example, where alternative antibiotics are not sufficiently effective.
However, they’re over-used in the same way as antibiotics are. They have been linked with adverse side effects that have been reported over time. The FDA has issued numerous warnings on their use. Many label modifications are required, and some fluoroquinolones have warnings in the black box.
What antibiotics are referred to as fluoroquinolones
These include Ciproofloxacin (Cipro), gemifloxacin (Factive) and Levofloxacin (Levaquin), moxifloxacin (Avelox) Norfloxacin (Noroxin), and ofloxacin (Floxin).
What is fluoroquinolone toxicity syndrome?
Signs and Symptoms
Certain side effects of fluoroquinolone medicines have been proven to be extremely dangerous permanently and irreversible. These include adverse effects on the cardiovascular and central nervous systems, musculoskeletal systems and the central nervous system. Other Cipro toxicity symptoms include:
– Mitochondrial dysfunction and DNA damage
– Brain fog
– Peripheral Neuropathy
– Blurry Vision
– DNA Damage
– Anxiety/depression related to Gaba, Gut Damage and the impact
– Tendonitis
– Muscle Atrophy
– Reflexes are heightened
The first signs of Cipro Toxicity include lower back pain, tendonitis tendon rupture, arthralgia as well as pain in the extremities. gait problems, neuropathies associated with depression, paraesthesia fatigue, memory impairment, sleep disorders, and impairment of hearing sight, taste and smell. Fluoroquinolones may increase the risk of peripheral neuropathy by 47% over time.
Ciprofloxacin was shown to affect the topology of mitochondrial DNA and prevent normal maintenance and transcription. Mitochondrial damage to tenocytes as a result of fluoroquinolone treatment could be involved in tendinitis or tendon rupture. It can also lead to fatigue or inflammation.
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